{"id":2667,"date":"2025-10-25T15:26:20","date_gmt":"2025-10-25T08:26:20","guid":{"rendered":"https:\/\/museum.pctu.com.vn\/?p=2667"},"modified":"2025-12-12T10:23:27","modified_gmt":"2025-12-12T03:23:27","slug":"the-worlds-first-bioengineered-eye-transplant-2015","status":"publish","type":"post","link":"https:\/\/museum.pctu.com.vn\/index.php\/language\/en\/2025\/10\/25\/the-worlds-first-bioengineered-eye-transplant-2015\/","title":{"rendered":"The World\u2019s First Bioengineered Eye Transplant (2015)"},"content":{"rendered":"<p style=\"text-align: justify;\" data-start=\"64\" data-end=\"396\">A team of surgeons in <strong data-start=\"86\" data-end=\"100\">Manchester<\/strong>, northern England, successfully performed the <strong data-start=\"147\" data-end=\"198\">world\u2019s first bioengineered eye implant surgery<\/strong> for <strong data-start=\"203\" data-end=\"216\">Ray Flynn<\/strong>, an 80-year-old patient who had completely lost his central vision due to <strong data-start=\"291\" data-end=\"337\">dry age-related macular degeneration (AMD)<\/strong>\u2014the most common cause of blindness in developed countries.<\/p>\n<p style=\"text-align: justify;\" data-start=\"398\" data-end=\"745\">Flynn is now using a <strong data-start=\"419\" data-end=\"438\">retinal implant<\/strong> that converts video images from a tiny digital camera mounted on his glasses. Thanks to this implant, he is able to see white lines on a computer screen. Flynn expressed excitement and hope that his vision would continue improving, allowing him to resume everyday activities such as gardening and shopping.<\/p>\n<p style=\"text-align: justify;\" data-start=\"747\" data-end=\"1143\">The implant\u2014called <strong data-start=\"766\" data-end=\"778\">Argus II<\/strong>, manufactured by <strong data-start=\"796\" data-end=\"834\">Second Sight Medical Products Inc.<\/strong> (USA)\u2014was originally developed to restore vision in patients blinded by the rare condition <strong data-start=\"926\" data-end=\"950\">retinitis pigmentosa<\/strong>.<br data-start=\"951\" data-end=\"954\" \/>The surgery at <strong data-start=\"969\" data-end=\"1002\">Manchester Royal Eye Hospital<\/strong> is the <strong data-start=\"1010\" data-end=\"1054\">first Argus II implantation in the world<\/strong> for a patient with dry AMD, a condition affecting at least <strong data-start=\"1114\" data-end=\"1142\">500,000 people in the UK<\/strong>.<\/p>\n<p style=\"text-align: justify;\" data-start=\"1145\" data-end=\"1255\">Before surgery, Flynn still retained peripheral vision but had completely lost central vision. He explained:<\/p>\n<blockquote data-start=\"1256\" data-end=\"1410\">\n<p style=\"text-align: justify;\" data-start=\"1258\" data-end=\"1410\">\u201cI couldn\u2019t use my bank card in shops or at the bank. I couldn\u2019t pull weeds in the garden. Even sitting close to the TV, I still couldn\u2019t see anything.\u201d<\/p>\n<\/blockquote>\n<p style=\"text-align: justify;\" data-start=\"1412\" data-end=\"1536\">His four-hour operation was performed by Professor Paulo Stanga of Manchester Royal Eye Hospital. According to Dr. Stanga:<\/p>\n<blockquote data-start=\"1537\" data-end=\"1672\">\n<p style=\"text-align: justify;\" data-start=\"1539\" data-end=\"1672\">\u201cRay Flynn\u2019s vision is improving. He can now see outlines of people and objects. It is fair to say the procedure has been a success.\u201d<\/p>\n<h3 style=\"text-align: justify;\" data-start=\"1679\" data-end=\"1718\"><strong data-start=\"1683\" data-end=\"1718\">How the Bioengineered Eye Works<\/strong><\/h3>\n<p style=\"text-align: justify;\" data-start=\"1720\" data-end=\"2052\">The implant receives visual information from the miniature digital camera on the patient\u2019s glasses.<br data-start=\"1819\" data-end=\"1822\" \/>These images are converted into electrical signals and transmitted wirelessly to <strong data-start=\"1903\" data-end=\"1927\">a 60-electrode array<\/strong> implanted in the retina.<br data-start=\"1952\" data-end=\"1955\" \/>The electrodes stimulate the remaining retinal cells, which send visual information to the brain.<\/p>\n<p style=\"text-align: justify;\" data-start=\"2054\" data-end=\"2336\">Two weeks after the surgery, Flynn could already distinguish <strong data-start=\"2115\" data-end=\"2159\">horizontal, vertical, and diagonal lines<\/strong> on a computer screen.<br data-start=\"2181\" data-end=\"2184\" \/>To confirm that his vision came from the camera\u2013implant system rather than his natural eyesight, Flynn was asked to keep his eyes closed during testing.<\/p>\n<p style=\"text-align: justify;\" data-start=\"2338\" data-end=\"2492\">Although the implant does not provide detailed vision, early studies show that it can help patients recognize <strong data-start=\"2448\" data-end=\"2491\">door frames and the outlines of objects<\/strong>.<\/p>\n<p style=\"text-align: justify;\" data-start=\"2494\" data-end=\"2674\">Four additional dry AMD patients are scheduled to receive the implant at Manchester Royal Eye Hospital as part of a clinical trial.<br data-start=\"2625\" data-end=\"2628\" \/>The Argus II device costs around <strong data-start=\"2661\" data-end=\"2673\">\u00a3150,000<\/strong>.<\/p>\n<p style=\"text-align: justify;\" data-start=\"2676\" data-end=\"2846\">The trial is being conducted by the <strong data-start=\"2712\" data-end=\"2753\">Manchester Clinical Research Facility<\/strong>, funded by the <strong data-start=\"2769\" data-end=\"2818\">National Institute for Health Research (NIHR)<\/strong> and the <strong data-start=\"2827\" data-end=\"2845\">Wellcome Trust<\/strong>.<\/p>\n<p style=\"text-align: justify;\" data-start=\"2848\" data-end=\"2909\">Cathy Yelf, Chief Executive of the Macular Society, stated:<\/p>\n<blockquote data-start=\"2910\" data-end=\"3115\">\n<p style=\"text-align: justify;\" data-start=\"2912\" data-end=\"3115\">\u201cThese results are extremely encouraging, and we are closely following the progress of the clinical trials. This research may lead to a truly useful device for people who have lost their central vision.\u201d<\/p>\n<\/blockquote>\n<p data-start=\"3117\" data-end=\"3143\">According to Dr. Stanga:<\/p>\n<blockquote data-start=\"3144\" data-end=\"3254\">\n<p style=\"text-align: justify;\" data-start=\"3146\" data-end=\"3254\">\u201cDry AMD is common and currently untreatable. In Western countries, it is the leading cause of vision loss.\u201d<\/p>\n<\/blockquote>\n<p style=\"text-align: justify;\" data-start=\"3256\" data-end=\"3402\">The charity <em data-start=\"3268\" data-end=\"3288\">Fighting Blindness<\/em> estimates that <strong data-start=\"3304\" data-end=\"3340\">over 30 million people worldwide<\/strong> suffer from dry AMD, which accounts for <strong data-start=\"3381\" data-end=\"3401\">85% of AMD cases<\/strong>.<\/p>\n<p style=\"text-align: justify;\" data-start=\"3404\" data-end=\"3544\">Second Sight is now developing the <strong data-start=\"3439\" data-end=\"3477\">third-generation bioengineered eye<\/strong>, which they believe may one day allow patients to recognize faces.<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>A team of surgeons in Manchester, northern England, successfully performed the world\u2019s first bioengineered eye implant surgery for Ray Flynn, an 80-year-old patient who had completely lost his central vision&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[73,47],"tags":[],"class_list":["post-2667","post","type-post","status-publish","format-standard","hentry","category-global-healthcare","category-uncategorized-en"],"_links":{"self":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/2667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=2667"}],"version-history":[{"count":1,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/2667\/revisions"}],"predecessor-version":[{"id":2668,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/2667\/revisions\/2668"}],"wp:attachment":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=2667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=2667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=2667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}