{"id":2669,"date":"2025-10-25T15:24:29","date_gmt":"2025-10-25T08:24:29","guid":{"rendered":"https:\/\/museum.pctu.com.vn\/?p=2669"},"modified":"2025-12-12T10:32:28","modified_gmt":"2025-12-12T03:32:28","slug":"worlds-first-3d-printed-human-ear-successfully-transplanted-into-a-patient","status":"publish","type":"post","link":"https:\/\/museum.pctu.com.vn\/index.php\/language\/en\/2025\/10\/25\/worlds-first-3d-printed-human-ear-successfully-transplanted-into-a-patient\/","title":{"rendered":"World\u2019s First: 3D-Printed Human Ear Successfully Transplanted into a Patient"},"content":{"rendered":"

Doctors in the United States have carried out what seems like a scene from science fiction:
a replacement ear grown in a laboratory from a patient\u2019s own cartilage cells and a 3D-printed scaffold.<\/strong><\/p>\n

The groundbreaking surgery was led by Dr. Arturo Bonilla<\/strong>, founder and Director of the Microtia-Congenital Ear Deformity Institute in San Antonio, Texas.<\/p>\n

The procedure was performed as part of an early-phase clinical trial evaluating the safety and effectiveness of 3D-printed ear implants<\/strong> for patients with microtia<\/strong>, a congenital condition in which the external ear is small and malformed due to improper development.<\/p>\n

Currently, microtia patients typically receive ear reconstruction using cartilage taken from their ribs, or synthetic materials such as porous polyethylene (PPE).
The new technique produces a far more ideal ear for the patient:<\/p>\n

Entirely biological,<\/p>\n

Made from the patient\u2019s own cells,<\/p>\n

And with a shape and appearance that match the opposite ear much more closely than traditional rib-cartilage reconstruction.<\/p>\n

The new implant, called AuriNovo<\/strong>, was developed by 3DBio Therapeutics<\/strong> in collaboration with the Microtia Institute.<\/p>\n

The process involves scanning the patient\u2019s healthy ear in 3D to create a digital model, then collecting a small sample of their ear-cartilage cells and expanding them in the lab.
These cells are mixed with a collagen-based bio-ink and shaped into an external ear using a biodegradable 3D-printed mold that supports the ear as it develops according to the initial design.<\/p>\n

The clinical trial aims to include 11 patients<\/strong>, with procedures currently underway in California and Texas.
The first patient\u2014a young woman\u2014received her implant more than a month ago. Her incision has nearly healed, and the transplanted ear has integrated extremely well with her body.<\/p>\n

According to Dr. Bonilla, 3D-printed ear transplants also make the surgery far less invasive<\/strong> than traditional methods, since no rib cartilage harvest is required and the reconstructive steps are significantly simplified.<\/p>\n

The U.S. Centers for Disease Control and Prevention (CDC) reports that microtia affects 1 in 2,000\u201310,000 newborns<\/strong>, with varying degrees of deformity.
Risk factors include maternal gestational diabetes and diets low in carbohydrates and folic acid.<\/p>\n","protected":false},"excerpt":{"rendered":"

Doctors in the United States have carried out what seems like a scene from science fiction:a replacement ear grown in a laboratory from a patient\u2019s own cartilage cells and a…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[73,47],"tags":[],"class_list":["post-2669","post","type-post","status-publish","format-standard","hentry","category-global-healthcare","category-uncategorized-en"],"_links":{"self":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/2669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/comments?post=2669"}],"version-history":[{"count":1,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/2669\/revisions"}],"predecessor-version":[{"id":2670,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/posts\/2669\/revisions\/2670"}],"wp:attachment":[{"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/media?parent=2669"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/categories?post=2669"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/museum.pctu.com.vn\/index.php\/wp-json\/wp\/v2\/tags?post=2669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}